Sino-Australian Study: bitter melon hypoglycemic agents are expected to made of

Chinese people are familiar with the bitter melon hypoglycemic agents are expected to develop the raw materials. Shanghai Institute of Materia Medica Chinese Academy of Sciences announced yesterday, the Australian researchers in the bitter melon in a number of active compounds found in composition, with a treatment of diabetes application prospects. The research results have been published in the internationally renowned Journal "cell" magazine published in the latest issue of "Chemistry and Biology" on.

 

Bitter gourd as a stubbornly traditional Chinese medicine for hundreds of years of medication history. Was first documented in the Ming Dynasty blue-mao relegated to "Southern Yunnan Materia Medica," said the bitter gourd, "Qingshu, Qi and thirst quencher," while traditional Chinese medicine will beDiabetes is called Diabetes disease. Modern Chinese research many of the bitter medicine, but the main part of --- bitter melon hypoglycemic activity mechanism of chemical substances and its role, but it has not been clear. YE Yang Chinese Academy of Sciences research fellow of the Shanghai Drug Task Force concluded ancient and modern literature and previous research, through many years of research, from the bitter separation and identification of a series of new natural chemical composition. They and Australia Jiaer text (Garvan) Medical Institute, at the cellular level of body and animal body the first time explicitly: the plant, these natural ingredients have a lower blood sugar activity.

 

At present, the two sides of the bitter melon hypoglycemic mechanism of action studies have shown that the new discovery of these compounds can activate the human body and energy metabolism is an important protein --- adenosine monophosphate-activated protein kinase (AMPK). AMPK regulation of this protein, the body has energy metabolism and promote the role of glucose uptake, and to take effective measures to activate AMPK, is the treatment of type 2 diabetes, an important way, so bitter gourd may provide a new diabetes treatments.

 

Experts said China has always been bitter in the Medicinal and Edible Plants, and were isolated from this plant for antidiabetic activity of this class of compounds, the first time the molecular level, confirms the ancient classics to the bitter gourd herbal medicinal records, as well as the results of the study of modern pharmacology. Research group speculated that these compounds in human cells is through a novel signaling pathway play a role, the signaling pathway to the discovery of new ways to treat diabetes, inventions and other hypoglycemic drugs, will have extraordinary significance.

 

It is reported that drugs and Shanghai Jia Er Wen Institute has signed a cooperation agreement, in which the results further on the basis of the therapeutic effects of bitter melon hypoglycemic mechanism to conduct a comprehensive evaluation and deepen the research.