Short stature a high risk of suffering from arthritis,

According to "Science Daily" magazine reported that on the 13th, a new study shows that the general and arthritis-related genetic variation may also play an important role in height, height reduction and osteoarthritis (the most common type of arthritis ) increased risk.

 

According to the researchers speculated that a high or low figure may be due to various reasons resulting contact with osteoarthritis. Although the longer bones may produce greater damage stress joints, but the bones short and / or cartilage may be able to lead to fewer joints more vulnerable to injury. This study will not only enable people to find genes associated with osteoarthritis, but also to enhance the relevant officers of the general understanding of height.

 

In order to obtain these findings, which came from the United States and Europe, researchers in more than 35,000 human genome analyzed. The researchers initially more than 200 million impact of genetic variation were studied. It was found that these new mutations leading to an average difference in height produced approximately 0.4 centimeters. Based on the population and whether the individual contains one or two so-called higher-variant gene showed differences in height from 0.3 centimeters to 1.4 centimeters.

 

The study also found that in the scientists believe that will affect the growth and differentiation factor -5 variations in the human genome more intense. Growth differentiation factor is a -5 with legs and other long-bone growth cartilage proteins. Growth differentiation factor -5 gene mutations and bone development of the situation is very rare disorder, which is presently led to the Asian and Europeans suffer from hip and knee osteoarthritis is more common variations in the type.

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